Murphysboro · Est. Local
Raise a Glass
to the Good Stuff
Coffee in the morning. Cocktails after dark. Same warm table waiting for you — right here on Locust Street.
Our Story
Not Just Another Spot.
Your Spot.
Genes Tavern sits on Locust Street because this is where people are — and where they want to be. We opened our doors with one simple idea: serve good food, pour honest drinks, and treat everyone like a regular.
Whether you're grabbing a morning coffee before work, meeting friends for lunch, or settling in for an evening drink, the table's yours. No pretense. No rush. Just a place that feels like it belongs — because it does.
Murphysboro, IL 62966
The Vibe
A Place to Stay
Intimate Setting
Comfortable seating, warm lighting, and a layout that encourages conversation — whether you're here alone or with a crowd.
Day to Night
Mornings are for coffee and conversation. Evenings shift to craft cocktails and live music. The same room, two great vibes.
Community First
We source locally when we can, host local events, and believe a tavern should be the living room of its neighborhood.
Find Us
Come On In
We're right on Locust Street in the heart of Murphysboro. Look for the green door — you'll know you've arrived.
Murphysboro, IL 62966-2119
Fri–Sat: 11am – 12am
Sun: 12pm – 8pm
Send Us a Note
Have a question, event inquiry, or just want to say hello? Drop us a line.
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